Postdoctoral Fellow in Computational Systems Biology
Job Summary
The Computational Biology Group at CIC bioGUNE seeks highly skilled and motivated postdoctoral researchers to work on an exciting project that aims at the development of computational approaches for designing neuronal cell conversion protocols. The selected candidate will develop a computational platform to identify hierarchical combinations of cell fate conversion factors, which will in turn be used to engineer highly specialized neuronal subtypes for cell transplantation therapies in animal models of Alzheimer's disease, stroke, and epilepsy.
The selected candidate will be part of a Canadian federal grant project (NFRF) with international collaborators who will conduct experimental validation of the computational predictions to translate neuronal reprogramming into clinical practice.
The deadline for submission of applications is August 15th, 2026.
Job Description & Benefits
The Computational Biology Group at CIC bioGUNE seeks highly skilled and motivated
postdoctoral researchers to work on an exciting project that aims at the development of
computational approaches for designing neuronal cell conversion protocols. The selected
candidate will develop a computational platform to identify hierarchical combinations of cell
fate conversion factors, which will in turn be used to engineer highly specialized neuronal
subtypes for cell transplantation therapies in animal models of Alzheimer's disease, stroke, and
epilepsy. To achieve this goal, the candidate will combine a gene network-based approach with
a machine learning model (foundational model) to propose protocols for the sequential
induction of transcription factors to generate desired cell subtypes. The selected candidate will
be part of a Canadian federal grant project (NFRF) with international collaborators who will
conduct experimental validation of the computational predictions to translate neuronal
reprogramming into clinical practice.
The Computational Biology Group aims at establishing a solid infrastructure to develop
theoretical frameworks for computational modeling of biomedical problems, especially in the
areas of stem cell research, aging and disease modeling. The group closely collaborates with
leading national and international experimental labs with a particular interest in stem cell
research and regenerative medicine.
Essential skills and qualities:
• Ph.D. degree in computational biology, bioinformatics, biology, computer science,
physics or related disciplines
• Strong computational skills in at least one programming language (e.g. R or Python)
• A strong publication record in related fields
• Excellent communication and working knowledge in English
Ideal skills:
• Prior experience in computational systems biology
• Prior knowledge about transcriptional regulation and the prediction of cellular
conversion factors
• Experience working in a multi-disciplinary research environment
We offer:
• Opportunity to do highly interdisciplinary research to solve complex biomedical
problems within a dynamic research institution (CIC bioGUNE) and in collaboration with
internationally recognized partner
• An exciting international environment
The deadline for submission of applications is August 15th, 2026
