This job offer was closed at 2025-11-15
Postdoctoral position for ERC project hASTROCURE
Job Summary
The Arranz Lab - Laboratory of Humanized Models of Disease at Achucarro Basque Center for Neuroscience, is seeking a Postdoctoral Researcher to join hASTROCURE, a project funded by the European Research Council (ref # ERC-2024-COG - 01171591). Our lab focuses on understanding the complex role of human astrocytes in Alzheimer’s disease (AD). Using cutting-edge stem cell technologies, humanized in vitro models, and chimeric mice, our research aims to dissect how human astrocytes contribute to AD onset and progression. We are part of a vibrant neuroscience community and collaborate closely with national and international partners. Interested?
Job Description & Benefits
* Culture, maintenance, and amplification of human induced pluripotent stem cells (hiPSCs), and derived neural progenitors and astrocytes.
* Design and perform experiments using hiPSC-derived astrocytes and other CNS cell types.
* Establish, maintain, and analyze chimeric mouse models of AD.
* Perform molecular, cellular and imaging assays (sample processing, immunofluorescence, microscopy, etc).
* Analyze and interpret data; prepare reports, manuscripts, and presentations.
* Desirable:
* Prior experience with Alzheimer’s disease models and glia/astrocyte biology.
* Prior track record of peer-reviewed publications in relevant fields.
* Prior experience supervising students.
The successful candidate will focus on understanding the reactive states of human astrocytes, and how they contribute to AD, using humanized in vitro models and chimeric AD mice. The candidate will work closely with experts in bioinformatics & spatial omics. It is a full-time position, starting the 1st January 2026.
https://www.achucarro.org/job/postdoctoral-position-for-erc-project-hastrocure/
Job Details
Organization Contact
Application Details
Additional Requirements
Skills
A PhD and excellent academic record in Neuroscience, Cell Biology, Bioinformatics, or related field.
Previous experience in hiPSC differentiation to neural cells and astrocytes, and in vivo work (mouse models).
Programming experience (e.g., R, Python, MATLAB) and familiarity with relevant bioinformatics pipelines.
Experience with sample processing, immunofluorescence, and microscopy.
Strong analytical, quantitative and time-management skills.
Good/excellent written and spoken English; ability to write scientific reports and papers.
Strong motivation for learning; ability to work independently and as part of a team.
Desirable:
Prior experience with Alzheimer’s disease models and glia/astrocyte biology.
Prior track record of peer-reviewed publications in relevant fields.
Prior experience supervising students.
