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This job offer was closed at 2025-01-06

Fundación Biofísica Bizkaia

Postdoctoral Position in Antibody-Based Therapeutics at the UPV/EHU

Research Field: Biological sciences 
Sub Research Field:  

Job Summary

A postdoctoral position (3-month initial period, extendable to 3 years) funded by Worldwide Cancer Research is available in Dr. Edurne Rujas and Dr. José Luis Nieva’s group at Instituto Biofisika (UPV/EHU, CSIC) (www.biofisika.org), (Bilbao, Spain). This position offers a unique opportunity to contribute to cutting-edge research at the intersection of protein engineering, oncology, and drug delivery systems.
Research Focus
The current project is dedicated to advancing innovative approaches to overcome resistance mechanisms in cancer therapeutics. Specifically, it centers on developing “Backpacked-antibodies”, a novel platform combining antibodies with lipid nanodiscs for enhanced precision in drug delivery. This project aims to engineer next-generation biologics that integrate chemotherapy with immune-checkpoint blockade for superior antitumor efficacy.

Job Description

Key Responsibilities
The successful candidate will:
1. Lead the production of antibody-based molecules utilizing advanced protein engineering techniques.
2. Evaluate therapeutic efficacy in vitro and in vivo by generating xenograft mouse models and conducting detailed analyses of antitumor responses.
3. Play a pivotal role in setting research goals and preparing high-quality manuscripts and presentations for publication and dissemination at scientific meetings.
4. Collaborate on multidisciplinary projects and contribute to the laboratory's dynamic research environment.

Benefits

Comment/web site for additional job details

FP7 / PEOPLE / Marie Curie Actions

Research Framework Programme/
Marie Curie Actions 		No 
SESAM Agreement Number  

Job Details

Type of Contract Temporary 
Researcher profile First Stage Researcher (R1)  
Status Full-time 
Hours Per Week 38  
Company/Institute University of the Basque Country (UPV/EHU)/Instituto Biofisika 
Country SPAIN 
State/Province Vizcaya 
City Leioa 

Organization/Institute Contact Data

Organization Fundación Biofísica Bizkaia 
Organization/Institution Type Research Laboratory 
Faculty/Department/Research Lab Instituto Biofisika 
Country SPAIN 
City Leioa 
State/Province  
Postal Code 48940 
Street Barrio Sarriena s/n 
E-Mail edurne.rujas@ehu.eus 
Website http://biofisika.org/ 
Phone +34946018001 
Mobile Phone  
Fax  

Application Details

Envisaged Job Starting Date 2025-03-01 
Application Deadline 2025-01-06 
How To Apply e-mail  

Required Education Level

Required Education Level 1
Degree PhD or equivalent 
Degree Field Biological sciences 

Required Research Experiences

Required Research Experiences 1
Research Field Biological sciences 
Research Sub Field  
Years of Research Experience 4 

Additional Requirements

Skill

Qualifications
We are seeking a highly motivated postdoctoral researcher with:
• Expertise in protein engineering, particularly antibody design and production.
• Hands-on experience with in vivo animal work, including the generation and handling of xenograft mouse models.
• Background in protein expression and cell biology is desirable.
• Strong organizational and communication skills, with a proven track record of scientific publications.

 
Specific Requirements

Application Details
Interested candidates should send the following documents in a single PDF:
• A detailed CV.
• A cover letter describing their research interests and relevant experience.
• Contact information for two professional references.