PREDOCTORAL RESEARCH R1 - ERC CoG DORMATRIX - REGENERATION AND CANCER GROUP
Research Field: |
Biological sciences |
Sub Research Field: |
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Job Summary
PhD project in the field of Biotechnology, Chemistry, Biochemistry, Biomedical Eng., Chemical Eng., Materials Science or related
The Cipitria Lab – Bioengineering in Regeneration and Cancer at Biogipuzkoa Health Research Institute, San Sebastián-Donostia, Spain (https://cipitrialab.com) is looking for a doctoral researcher. In our group, we aim to understand how biophysical and biochemical properties of native extracellular matrix and synthetic biomaterials guide cell response in regeneration, cancer dormancy and bone metastasis. We are located within the structure University Hospital Donostia-Onkologikoa.
Funded by an ERC CoG grant (https://doi.org/10.3030/101123883), the main objective of DORMATRIX is to engineer breast cancer dormancy as a collective emergent phenomenon using biomaterials-based dormancy-on-a-chip devices. In this project, you will model in vitro breast cancer micro-units applying biophysical principles with novel biomaterials.
Job Description
DUTIES AND RESPONSIBILITIES:
Your tasks:
• Apply biophysical principles with novel biomaterials to model in vitro breast cancer micro-units.
• Hydrogel synthesis and development of microparticles with controlled physico-chemical properties.
• Culturing breast cancer cells in controlled 2D and 3D microenvironments.
• Monitoring breast cancer cell dynamics with advanced microscopy and time-lapse fluorescence life cell imaging.
• Collaborate in additional projects and become an integral member of our team.
• Our lab maintains an active part in Germany, as well as interaction with partners at the Max Planck Queensland Center (https://research.qut.edu.au/mpqc/). You will participate in regular consortium meetings and larger consortium events
Suggested reading:
Bakhshandeh, Heras et al, Science Advances (2024), in press;
Taieb et al, Lab on a Chip 23, 92–105 (2023);
Taieb et al, PLoS One 17, e0268297 (2022);
Young et al, Science Advances 10, eadj0975 (2024).
Benefits
• TYPE OF CONTRACT (LEGAL REFERENCE): One year Trainee Predoctoral Researcher
contract available, extendable to a maximum of 4 years (annual extensions)
• WORK SCHEDULE: Full time
• EXPECTED START DATE: December 2024-January 2025
• ANNUAL GROSS SALARY: 20.808€ gross per year
The remuneration shall be based on the candidate’s commitment and merit, as well as how suited they are for the role. The worker must comply with the operating rules set by the Biogipuzkoa Institute in terms of commitment, duties, working hours, leave entitlements, etc.
Comment/web site for additional job details
https://gestiononline.bioef.eus/ConvocatoriasPropiasBiogipuzkoa/es/Convocatorias/VerConvocatoria/2972